John Doe is one of the major characters in the Embalming series. He is the 6th of the 8 Specialized Types created by Dr. Richter known as "The Ultimate Eight". He is also the murderer of Elm L. Renegade. John Doe was brought back as a Frankenstein but went berserk shortly after. He killed Elm and tore of the right leg of Ashuhito. Since Elm was Ashuhito's girlfriend, she was brought back as the 7th of the eight specialized types by Dr. Richter and lost all of her memories. John however has no memory of this or anything of his past. Dr. Peaberry knows John Doe's past but she refuses to say anything other than she wants him dead.
Extremely powerful, John was able to stop the full force of a modified Frankenstein, and tear many more apart, with his bare hands. He has scars in the form of a briar cross on his left palm and on his chest, out of which comes a pressurized blast of blood capable of tearing apart flesh, steel, and anything else in his way.
John's Specialized Circulatory System allows him to make and eject seemingly endless amounts of blood. With it, he was able to completely flood the London sewers and turn the Thames red, killing dozens of Frankensteins in the process. He can also shoot a powerful blast of blood from his scars which gives them a cross-like shape. Those that see this attack call it the "Briar Cross".
John comes off as extremely selfish and his only goal is to gain a Frankenstein Bride. He plans to accomplish this by roaming around, killing Frankensteins and scientists for other people in exchange for the body parts of beautiful women. He enjoys tormenting Little Rose, and prefers people who speak honestly then those who pretend to be innocent.